SELECTIVE ISOLATION OF EXTRACELLULAR VESICLES FROM MINIMALLY PROCESSED HUMAN PLASMA AS A TRANSLATIONAL STRATEGY FOR LIQUID BIOPSIES

Selective isolation of extracellular vesicles from minimally processed human plasma as a translational strategy for liquid biopsies

Abstract Background Intercellular communication is mediated by extracellular vesicles (EVs), as they enclose selectively packaged biomolecules that can be horizontally transferred from donor to recipient cells.Because all cells constantly generate and recycle EVs, they provide accurate timed snapshots of individual pathophysiological status.Since b

read more

EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia

Background: With the capacity to modulate gene networks in an environmentally-sensitive manner, the role of Chairs w/Table Set (3/CN) epigenetic systems in mental disorders has come under intense investigation.Dysregulation of epigenetic effectors, including microRNAs and histone-modifying enzymes, may better explain the role of environmental risk

read more



Predicting Hybrid Performances for Quality Traits through Genomic-Assisted Approaches in Central European Wheat.

Bread-making quality traits are central targets for wheat breeding.The objectives of our study were to (1) examine the presence of major effect QTLs for quality traits in a Central European elite wheat population, (2) explore the optimal strategy for predicting the hybrid performance for wheat quality traits, and (3) investigate the effects of mark

read more